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Orforglipron, an oral small-molecule GLP-1 receptor agonist for obesity treatment
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimers disease
These approaches may accelerate the development of new peptide drugs
With these results in hand we became convinced that a clinically useful small molecule analog could be designed that possessed the important characteristics of metabolic stability, extended half-live, BBB penetrability and the capability to enhance cognitive functioning
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