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Numerous randomized scientific studies in populations at high risk for iron deficiency anemia and goiter came to the inference that the combined treatment with iodine and iron is better than the iodine treatment alone (121124)

In iodine-deficient countries, iodine-deficiency diseases predominate in the structure of thyroid disease, and in regions with normal or greater iodine supply, there is an increase in thyroid disease (48)

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Biochemically, silica stimulates rice to rapidly produce defense compounds such as phenolics, flavonoids, lignin, callose, and plant toxins, while also increasing the activity of defense enzymes such as peroxidase, phenylalanine ammonia-lyase, polyphenol oxidase, lipoxygenase, and -1,3-glucanase [27]

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