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With newer GLP-1-based therapies now emerging, the field has an opportunity to test whether different drugs in this class have distinct effects on aging biology and to identify which patients may benefit most." Much larger clinical trials will be needed to confirm the results, determine how long any benefits last, and identify the most effective treatment schedules for both people with HIV and the broader population

The primary lipid change seen with the initiation of insulin therapy is a lowering of TGs, which correlates with a lowering of glucose and hemoglobin A1c

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Its also important to screen for any history of eating disorders, as the appetite-suppressing effects of GLP-1s may pose risks for certain individuals