"This is where I am very cautious," Hatipoglu says
This conventional method, for some long peptides and peptide fragments with strong hydrophobicity, is easy to form beta-sheet secondary structure through intramolecular hydrogen bond during synthesis, thereby causing shrinkage of resin and resulting in coupling difficulty
Prakash V, Martin-Belloso O, Astley SB, Braun S, Mcmahon H, Lelieveld H
moreover, the model was robust toward exclusion of data with high residuals, i.e., weighted residuals above 4 and below 4 (Table S4 in the ESM)
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Acting as the conductor, peptides are chemicals that sit on the top of multiple hormonal cascades