Retatrutide 12 mg produced 24.2% mean body-weight loss at 48 weeks in the Phase 2 obesity trial (Jastreboff et al., NEJM 2023) [3][4]
For research framed around different cognitive mechanism classes, see the Semax hub (a heptapeptide derived from ACTH 4-10 with proposed BDNF-mediated mechanisms the closest cognitive-category neighbor in the catalog, though a different mechanism class)
In addition to fat reduction, it enhances circulation and lymphatic drainage, supports metabolism when combined with a healthy lifestyle, and promotes cellular repair
Here is what our patients actually experience
Retatrutide's Phase 2 trial, published by Jastreboff et al
Kainer MA, Reagan DR, Nguyen DB, et al