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Patients should seek urgent medical attention if they experience severe or persistent abdominal pain, which may be a symptom of pancreatitis or gallbladder disease

It is also contraindicated for those with a history of pancreatitis, as the medication may increase the risk of this condition

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However, due to the limitations of medical knowledge at the time, the primary focus was on patient survival rather than long-term complications (16)

IGF-1 Elevation Increased HGH stimulates the liver to produce IGF-1, the downstream mediator responsible for many of growth hormone's tissue-level effects

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