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87 In addition to systemic effects on glucose metabolism and insulin sensitivity, GH may contribute to diabetes-associated complications, such as diabetic retinopathy and diabetic renal disease, through localized expression and autocrine/paracrine effects in tissues, 88,89,90,91,92,93 although published research in these areas is limited

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The total number of immune-positive cells in each image was quantified using ImageJ software (National Institutes of Health) by a technician who was blinded to the identity of the samples on each slide

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