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2013;54(5):3333-3339.23599328 Sechi G, Deledda MG, Bua G, et al

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Gallbladder-related adverse events, including cholelithiasis and cholecystitis, have been reported more frequently in patients receiving semaglutide compared to placebo in clinical trials, with an incidence of approximately two to three percent

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It is a useful reminder that stimulating endogenous GH is not automatically equivalent to, or stronger than, giving GH directly and that the peptides documented effect sizes are modest even in the population where it was best studied