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One study showed that 50 children with ADHD and other behavioral issues had significant improvement with 6 months of 200 mg magnesium supplementation (36) Vitamin B6: Has been studied along with magnesium to reduce hyperexciteability, aggressiveness, and behavioral problems in school aged children (37, 38)

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They can also support overall wellbeing where appropriate

Older adults, as the ability to absorb B12 from food decreases with age

Human trials are shorter but show improvements in biological aging markers, inflammation levels, and cellular stress response [5]