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In temporal lobe epilepsy, AQP4 is paradoxically upregulated despite the loss of -syntrophin, suggesting maladaptive redistribution and impaired buffering [411]

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What we do NOT know The gaps here are large enough that unknown long-term safety should itself be treated as a risk, not a green light: No long-term human safety data

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Additional studies are required to elucidate the role of TFR2 in TNBC in the future

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