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Metabolic profiling of human plasma reveals the activation of 5-lipoxygenase in the acute attack of gouty arthritis

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Remarkably, this proinflammatory ATM polarization phenotype was also observed in PAR2-R38E when compared with PAR2-WT mice (Figure 4B and Supplemental Figure 6B)

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Slack E, Hapfelmeier S, Stecher B, et al