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In Parkinsons disease (PD) patients, applying anodal tDCS to the prefrontal cortex (PFC) during walking immediately improves gait variability, processing speed, and executive control (Conceio et al., 2021)

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In turn, this prevents polyubiquitination and proteasomal degradation of Nrf2 protein stabilizing its levels ( Besides, SFN can potentially alleviate/break the vicious cycle of oxidative stress and gut dysbiosis shown in Figure 4

Aman, Y., Qiu, Y., Tao, J