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Fourteen days after SNI surgery, compared with those in the sham group, the mice in the SNI group presented heat hyperalgesia after intraplantar vehicle administration (Fig

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The study period was also the data analysis period, given that our research was a cross-sectional study

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PMCID: PMC6213308

Notably, chronic stress can trigger epigenetic modifications, reprogramming astrocytes into disease-associated reactive states with distinct molecular profiles compared with normal astrocytes 9,11