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Furthermore, three studies showed that SGLT-2 inhibitors reduced diabetes mellitus (DM) onset, though statistical significance was not achieved (p-value = 0.08, SMD: -2.21, CI: [-5.11, 0.69])

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329,330 Direct insulin signaling in neurons can reverse features of DN independent of glucose levels

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[13] Tan PK, et al

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Liver disease and cancer

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