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Patients should be counseled about the importance of adherence to the weekly dosing schedule

In clinical trials, lower doses of Ozempic resulted in a mean increase in heart rate of two to three beats per minute. Some patients have found the experience uncomfortable

15% At 5mg maintenance dose Average body weight reduction after 72 weeks

1 Introduction Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by impaired hypothalamic development and function with an estimated incidence of 1 per 20,000 newborns ( Patients with PWS experience complex nutritional, neurodevelopmental, metabolic and behavioral changes that drive obesity development ( Obesity management in PWS typically includes a calorie-restricted diet, strict control of food access, regular physical activity and behavioral interventions ( 2 Case series 2.1 Patient 1 A 28-year-old female with PWS, resulting from uniparental disomy, was evaluated at our Endocrinology Unit