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observed a large amount of cell apoptosis and destruction of EP in the IVD of the spondylosis model compared with naturally aged IVD

When P-15 is added in scaffold material, it results in a significantly higher gene expression of alkaline phosphatase (ALP), BMP-2 and BMP-7 [235]

This powerful compound has been found to stimulate the proliferation and migration of various skin cells, including keratinocytes, fibroblasts, and endothelial cells, which are crucial for the wound healing process

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The activation of protein kinases may lead to the phosphorylation of transcription factors, which are proteins supporting gene expression