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It is evident that one-carbon metabolism has a potential role in regulating cell fate during metabolic stress and can be a potential therapeutic target for enhancing antitumor effects [231]

Alexis has received grant/research support (funds to institution) from Leo, Novartis, Almirall, Bristol-Myers-Squibb, Celgene, Menlo, Galderma, Bausch Health, and Cara

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The medications work through different mechanisms and can be additive

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