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In the brain, mitochondrial injury contributes to progressive loss of gray- and white-matter integrity, especially in frontal and limbic regions that regulate emotion and cognition [22]

[DOI] [Google Scholar] 189.Adedapo A.A., Mogbojuri O.M., Emikpe B.O

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[6] [10] The correct tier is therefore investigational, development halted for lack of demonstrated efficacy not approved, and emphatically not a compound that succeeded in trials