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In scientific updates, a new study (GLP-1 Receptor Agonists or SGLT2 Inhibitors and Nonarteritic Anterior Ischemic Optic Neuropathy) suggests that taking a GLP-1 may be associated with an increased risk of developing NAION, a type of eye stroke that can cause sudden, permanent blindness

In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1

Bibcode:2021PLoSO..1650827J

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While the peptide holds immense promise, it is crucial to consider individual health conditions, potential side effects, and ongoing research findings