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A cross-sectional analysis found that MeDi adherence was associated with increased gut microbial diversity and higher levels of short-chain fatty acids, metabolites linked to reduced inflammation and improved vascular health (De Filippis et al., 2016)

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In contrast, the United States regulates probiotics under multiple pathways (foods, dietary supplements, drugs, biologics), using Generally Recognized As Safe (GRAS) notices for food uses and more demanding drug/biologic pathways for LBPs intended to treat or prevent disease (521)

FDA is working with its state regulatory partners and will continue to communicate with compounders regarding these concerns

In skin biology, theres interest in glutathione because of its proposed roles in: Inhibiting tyrosinase (an enzyme crucial to melanin production) in theory reducing pigment formation

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