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This is because flavonoids with catechol groups, such as EC and CH, lacks conjugation to the 3-OH group in C-ring which shield such molecules to form ( p )para-quinone methides, and thus, flavonoids with these structural properties restrict their oxidation at the B-ring by the tyrosinase enzyme 104

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Satisfactory therapeutic effects were also observed with the combined use of olaparib and ABT-263 [137]

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In patients with very low GH output, the stronger stimulation from GHRP-2 may be needed to produce a meaningful GH pulse