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The question that matters clinically is whether a given patient is a good candidate, what the right protocol looks like for their specific goals and lab results, and whether they have access to a supervised framework that can catch the small number of patients for whom these compounds are not appropriate before they start rather than after

2.3 Evidence grading and strength of recommendations To address the need for clinical applicability, a grading system has been introduced to assess the strength of the recommendations presented in this review

placebo, patients had mean body weight reductions of 8.4 kg vs

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