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Compounding pharmacies expand this further with Bi-Est formulations (estriol and estradiol combinations), customizable progesterone preparations, and testosterone or DHEA additions when clinically indicated

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The quantification of PSR staining (Figure 3G) showed a marked increase in interstitial fibrosis in iron-overloaded hearts and a considerable reduction of fibrosis in the hearts from the amlodipine-treated group