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By targeting multiple pathways involved in appetite regulation, energy balance, and glucose metabolism, this combination could offer superior efficacy compared to single-agent therapies
Based on reported side effects, Melanotan 1 has the narrower, milder profile because it targets a single receptor
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THP-1 monocytes were maintained in RPMI 1640 medium (Gibco) with 10% FBS, 2 mM L-glutamine and 50 M 2-mercaptoethanol (Gibco)
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