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Menstrual cycle phase affects appetite and water retention, creating weekly fluctuations that make progress tracking more challenging

Among Semaglutide comparisons, surgical rates showed no significant differences between Phentermine/Topiramate (HR 0.18, 95% CI 0.021.55, p = 0.08)

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In cases of refractory IIH, traditionally challenging to manage, the tirzepatide group showed a 23.2% reduction in risk at three months (RR 0.768, 95% CI 0.5920.997, p=0.046), maintaining a 20.5% risk reduction at 24 months (RR 0.795, 95% CI 0.6540.965, p=0.019)