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Males were dosed for 4 weeks prior to mating, and females were dosed for 2 weeks prior to mating and throughout organogenesis until Gestation Day 17

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How to Talk to Your Doctor About Split Dosing If you are having side effects that wont go away, you should talk to your doctor

The strategy is straightforward: choose foods that are low in sulfur compounds, easy to digest, and supportive of healthy gut transit

Fifth, the inclusion of both RCTs and observational studies introduces potential bias due to differences in design, particularly confounding and selection bias in observational data, which may distort pooled effect estimates