Creating topical GHK-Cu serum 1% GHK-Cu serum (common strength): 50mg GHK-Cu powder Mix with 5g (5ml) carrier (hyaluronic acid serum, gel) Creates 1% concentration Apply daily to face 2% GHK-Cu serum (stronger): 50mg GHK-Cu powder Mix with 2.5g carrier Creates 2% concentration More powerful but can irritate Carrier options: Hyaluronic acid serum (best) Aloe vera gel Water-based serum Niacinamide serum How to make: Purchase quality carrier serum Add GHK-Cu powder to serum Mix thoroughly until dissolved Store in dark bottle Refrigerate Use within 30 days Topical application protocol Daily application: Cleanse face thoroughly Apply 2-3 drops serum to face and neck Massage gently until absorbed Morning and/or evening Follow with moisturizer if desired Where to apply: Entire face Neck and dcolletage Around eyes (careful, avoid in eyes) Forehead wrinkles Any area with aging concerns Expected results: Week 4-6: Skin texture improving Week 8-10: Visible firmness increase Week 12+: Wrinkle reduction, tone improvement Combining with skincare: Use GHK-Cu before moisturizer Can combine with retinol (see timing below) Compatible with vitamin C, niacinamide Use SPF during day (always) See our can you use peptides and retinol together , hyaluronic acid peptide , and copper peptides ruined my skin guide
Peripheral effects Via the AMY2 and AMY3 receptors Cagrilintide acts peripherally: Slowing of gastric emptying , stronger than with GLP-1 Suppression of postprandial glucagon , helps control postprandial glycemic spikes Modulation of bone remodeling (via AMY3), a neutral effect, but clinically monitored Synergy with GLP-1 (the mechanistic basis of CagriSema) The main innovation is the complementarity with the GLP-1 pathway : GLP-1 suppresses appetite via the arcuate nucleus of the hypothalamus (POMC neurons, AgRP/NPY inhibition) Amylin suppresses appetite via the area postrema (CGRP-like neurons) Two independent centers, two independent mechanisms
Journal of Medical Biochemistry 34, Pages 151159, ISSN (Online) (2015)
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While BPC-157 is excellent for dense connective tissues, TB-500 excels at repairing muscle and surface tissues
Always follow your veterinarians instructions when administering peptides to ensure proper dosage and timing
