However, its important to ensure your hypothyroidism is properly treated with appropriate thyroid hormone replacement first, as medication alone cannot fully compensate for untreated hypothyroidism
Severe rash
A history of medullary thyroid cancer or MEN 2 Prior pancreatitis or certain gallbladder diseases Significant or chronic kidney disease Uncontrolled gastrointestinal disease Pregnancy, breastfeeding, or plans to become pregnant soon Patients should also disclose mental health history and any disordered eating patterns
Recommended activities for best results: Walking or light cardio Low-impact but effective for weight loss Strength training Helps preserve muscle while losing fat Yoga or Pilates Great for stress reduction and body toning We offer personalized fitness guidance to complement your weight loss plan
This guide breaks down the pharmacology, the mechanistic contrast, the head-to-head trial evidence (including the 2025 SURMOUNT-5 results), what enthusiast and research communities online are saying, and the practical realities of sourcing both compounds in Canada
Reduce your dose gradually Tapering typically happens over several weeks to a few months
