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Decrease in ovarian reserve through the Inhibition of SIRT1-mediated oxidative phosphorylation

Using in vivo and ex vivo ischemia-reperfusion models, ozone treatment was shown to reduce myocardial injury by regulating ferroptosis-related proteins and transcription factors, particularly enhancing Nrf2 nuclear translocation, thereby exerting cardioprotective effects ( 3.1.5 Mechanisms of ferroptosis in myocardial ischemia-reperfusion injury In pathological conditions such as myocardial ischemia-reperfusion injury, the Nrf2/Keap1 pathway becomes dysregulated, leading to the dissociation of Nrf2 from Keap1 and its subsequent translocation into the nucleus

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11.2 What GLP-1 Therapy Does Change GLP-1 receptor agonists consistently: Reduce caloric intake Narrow food volume Alter dietary patterns Increase early satiety Promote rapid weight loss in responders These behavioural and physiological changes shift nutritional exposure

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