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Key Takeaways Glycolic acid (AHA) works on the skin's surface best for dull, dry, ageing, or uneven skin Salicylic acid (BHA) works inside the pore best for oily, congested, acne-prone skin The core difference is solubility: glycolic is water-soluble, salicylic is oil-soluble You can use both, but alternate them never layer two acids in the same session Always wear SPF when using glycolic acid it increases sun sensitivity Start low, go slow: begin with 12 uses per week and build from there When in doubt, patch test first FAQ: Salicylic Acid vs Glycolic Acid Q: Which is better for acne salicylic acid or glycolic acid