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The generation of the TMA was retrospective and patient information was de-identified, so a written informed consent was not required as deemed by COMIRB, as per the ethical standard defined by the Declaration of Helsinki

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In addition to its function as an activator of type I IFN synthesis and autophagy, STING can also activate the NF-B pathway in a TBK1-IKK-dependent or TBK1-independent manner that involves DNA damage response factors ataxia telangiectasia mutated (ATM) and poly(ADP-ribose) polymerase 1 (PARP1) (146148)

10.13193/j.issn.1673-7717.2014.06.072 72 YuanR.TaoX.LiangS.PanY.HeL.SunJ.et al (2018)