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For patients who have plateaued on semaglutide or who respond better to dual-agonist therapy, transitioning to a tirzepatide glycine B12 blend may provide the additional efficacy needed

Further analysis suggested that the peptide may have increased the ratio of Bcl-2/Bax, and potentially decreased cleaved caspase-3 and PARP levels, two markers of cell death

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However, all patients should undergo a consultation to assess suitability, especially those who are: Pregnant or breastfeeding Undergoing treatment for chronic illness Allergic to any components of the injection Possible side effects are rare and may include minor irritation at the injection site or mild nausea

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Medical Conditions: People with a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer) should avoid semaglutide