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Side-effects range from mild (nausea, injection-site discomfort) to serious and even life-threatening (allergic reactions, liver injury, systemic inflammatory response, endotoxin-related events)

Report a history of diabetic retinopathy or significant vision changes

The Takeaway: This is a classic case of the "Patent Cliff"where exclusivity ends, competition begins, and consumer access improves drastically

Avoid touching the injection site for 6 hours after your treatment

For people who prefer not to inject, this is a meaningful alternative

Note that Januvia offers certain coupon programs for patients who have difficulty affording the co-payment they need to make