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High Arg1 expression is associated with M2 polarization and exerts immunosuppressive effects, whereas low IDO1 expression is closely associated with loss of tolerance and enhanced pro-inflammatory responses (84)
Furthermore, TH17 cells impede the maturation and survival of oligodendrocytes (OLs), as well as induce their apoptosis [266, 267]
Invest 121 , 13291343 (2011)
While rosacea is a chronic skin condition, its progression can often be slowed or even put into remission by addressing the root causes early