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Stimulation of muscle resident fibroblasts with this factor increases their collagen and fibronectin production, which results in increased interstitial fibrosis [4143]

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Similarly, the uncontrolled release of GO into the environment could lead to issues related to its persistence, bioaccumulation, and potential toxicity to aquatic life and other organisms 223,325

Biochim Biophys Acta 1802(1):2944