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A double-blind, placebo-controlled trial in 95 patients with irritable bowel syndrome or inflammatory bowel disease and normal B12 levels found no significant improvements in fatigue, although B12 levels increased in the B12 group who received 1000 g per day per os (p.o.) for 8 weeks (form not reported)

The 250500 mcg subcutaneous range used in current research contexts sits below the 1 mg clinical trial dose, partly because subcutaneous bioavailability differs from the oral administration used in some trial arms

Baguley DM, Caimino C, Gilles A, Jacquemin L

Scientific classification: Despite its appearance in Peptides UK catalogues, 5-Amino-1MQ is not an amino-acid-chain peptide

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