Enhancement of glucose-stimulated insulin secretion by PF-06882961 was concentration-dependent and was also observed following oral dosing with similar efficacy when compared to administration by IV infusion (Fig
Prognostic significance of amino-acid transporter expression (LAT1, ASCT2, and xCT) in surgically resected tongue cancer
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By regulating gastric emptying, GLP-1 not only aids in short-term appetite control but may also contribute positively to long-term energy balance and weight management
While the study establishes a compelling systemic role for SLC25A45 in fuel switching, important questions remain regarding the tissue-specific contributions of this pathway and how carnitine biosynthesis and utilization are differentially regulated across dietary, disease, and sexually dimorphic contexts
