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For example, antibiotics that induce ROS, like -lactams or aminoglycosides, often cause bacteria to up-regulate the pentose phosphate pathway for NADPH production, which feeds GSH

Their data showed that, while the octanol-water partition coefficient (LogP) increased linearly with molar volume, the membrane-water partition coefficients (LogB), increased initially with LogP for the smaller molecules, but then followed a more parabolic relationship with respect to larger V m

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Such modifications may impede neuronal communication, potentially leading to depressive symptoms

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