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Literature search was conducted on PubMed, Scopus, Web of Science, and Embase using a combination of the keywords gut microbiota, gut microbiome, gut-brain axis, gut-kidney axis, gut-brain-kidney axis, chronic kidney disease, dysbiosis, therapy, metabolites, and neuroinflammation. Relevant studies were selected and synthesized in this narrative review

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Decrease in inflammation

134,135,136 While dividing the daily caloric intake between two meals per day is a common practice for healthy adult dogs, recent data observed that once-daily feeding of dogs was associated with a lower incidence of cognitive dysfunction, and lower odds of having gastrointestinal, dental, orthopedic, kidney/urinary, and liver/pancreas disorders

Conroy M, Chang YM, Brodbelt D, et al