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Other common metastatic sites include the lungs, liver, bones, and brain
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This sensitivity is essential for the bodys ability to respond appropriately to the presence of stool in the rectum, thus preventing involuntary leakage and maintaining continence
However, at the SNAC dosage of 300 mg per tablet of oral semaglutide, it is well below the toxic dose of 1.8 g/kg/day observed in monkeys, where it caused nausea and diarrhea (133)