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Mechanistically, tirzepatide treatment led to activation of brain areas that are known to control appetite and feeding behavior in rodents [67], a finding that is consistent with another GLP-1 analogs (semaglutide) activity in the brain [68]

Food and Drug Administration (FDA) include semaglutide (sold as Ozempic and Wegovy), liraglutide (Saxenda and Victoza), and tirzepatide (Zepbound), a dual GIP/GLP-1 receptor agonist

doi: 10.3389/FENDO.2024.1335435 58 KoelemanBPCLieBAUndlienDEDudbridgeFThorsbyEde VriesRRPet al

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