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The gradient started at 5% B (held for 2.5 min) and was linearly increased to 30% B within 37.5 min, to 50% B within 10 min, then to 85% B within 5 min (held for 3 min)

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Step 4: Draw Solvent into Syringe Open a new, sterile syringe and attach a sterile needle

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