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difficile is the leading aetiological agent of diarrhoea in healthcare settings, with almost half a million cases reported in the United States alone in 2011, of which 29,300 were fatal (Lessa et al

While vitamin B12 deficiency is rare and most people get enough B12 from their diets, some people may be at greater risk of low B12 levels, including vegetarians and vegans, older adults and people with digestive system conditions, such as Crohn's disease and celiac disease

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The pen may be stored at room temperature (up to 86F or 30C) or refrigerated during this 30-day period

Additionally, some patients may experience changes in their dietary habits when starting these medications, such as reduced appetite or altered food choices, which can further contribute to digestive issues