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Liangshu Feng, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Stress, poor sleep, alcohol, sun exposure, environmental toxins, and intense exercise all lower levels over time

In the D-Gal + FOXO4-DRI group, mice also received D-galactose injections and, after 4 weeks, were given intraperitoneal injections of FOXO4-DRI (5 mg/kg, MCE, HY-P4157) every 2 days for 4 weeks, followed by tissue collection

More options could also help alleviate the shortages seen in the U.S

Exercise timing interacts with the supplement protocol