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10.1200/JCO.2002.20.3.751 18 GeislerJ

Dose-Response Patterns Phase 1/2 trials tested CJC-1295 with DAC at single doses ranging from 30-250 mcg/kg (PMID 16352683)

Most patients can minimize these side effects by starting with a low dose and gradually titrating upward

Typically in a steady state, Mounjaro moves between 40% more than the steady state average and roughly 30% less

However, there is a pool of loosely chelated iron in cells: while most cellular iron is bound to heme, there is soluble and chelatable ferrous iron in the cytoplasm which forms the labile iron pool [23]

Consistent with what Arab Dolatabadi and Mahboubi found, the present study found that injecting DEX considerably raised TC, TG, LDL, and VLDL while lowering HDL associated with the negative control group (Oudraogo (2020)