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In addition to the various resident bacteria performing different functions, the intestinal flora's active metabolites also have complex functions

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Surgical treatment Sun et al.44 tested 48 patients with chronic constipation and demonstrated that patients with MC are more suitable for ileosigmoidal anastomosis (ISA) than cecorectal anastomosis (CRA)

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In many hypoxic tumors, mitochondrial respiration is selectively preserved or reprogrammed to adapt to the dual pressures of low oxygen and high proliferative demand, and glutamine metabolism contributes to this fine-tuned metabolic plasticity (97)