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A widespread and silent condition MASH, formally known as nonalcoholic steatohepatitis (NASH), affects people with metabolic conditions like obesity and type 2 diabetes

Variants in the SLC22A5 gene result in an absent or dysfunctional OCTN2 protein

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and Novo Nordisk, but the race is on to develop the best-in-class GLP-1 with improved muscle retention, reduced side effects, and patient-friendly formulations

To confirm this, the antibodies were given intravenously (i.v.) to human FcRn transgenic mice (Tg32), preloaded with pooled human IgG (IVIg) to introduce natural competition for receptor binding (Fig