The burden of proof shifts
Its more stable, more potent and better absorbed
Once opened, discard unused solutions
In this sense, fatigue represents one of the main extraintestinal manifestations of IBD, being associated with depressive behavior and impacting sociability and other life spheres, hence the amelioration of this parameter can have important impacts in mental health and other habits, as seen in this study (Pans et al., 2023)
Also, ginger reduced the risk of migraine-related nausea and vomiting (179)
A prospective randomized controlled study evaluating the potential preventive effect of L-carnosine on acute oxaliplatin neurotoxicity in patients with colorectal cancer enrolled 65 patients and showed that the levels or activities of NFB (27%) and TNF- (36.6%) were significantly decreased in the group receiving the FOLFOX-6 regimen (oxaliplatin, 5FU, and leucovorin) with daily oral L-carnosine (500 mg), while L-carnosine as a supplement for patients with CIPN alleviated neuropathic symptoms by decreasing oxidative stress (Nrf-2 and NF-B pathways) and apoptosis (caspase-3 activity) [144]
