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Increased iron in brain tissue causes reactive oxygen species (ROS) formation via Fenton reaction, inducing ferroptosis and finally leading to neurodegeneration (Kim et al., 2015

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IV nutrient therapy may help manage some of these effects: Fatigue : B vitamins, magnesium, and amino acids delivered intravenously can help address fatigue, which affects up to 90% of cancer patients

This downregulation leads to smitochondrial dysfunction and activation of the adenosine receptor A2A (Adora2a)/Ras-associated protein 1 (Rap1) signaling pathway, thereby inducing VSMC ferroptosis and ultimately exacerbating vascular calcification [25]

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