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In CC531, a colon cancer cell line, GT was upregulated in a time and dose-dependent manner to irradiation

A 2011 trial of 40 women with Crohn's disease found that 80% of participants taking 4.5 mg of naltrexone daily for 12 weeks had less severe symptoms, and 33% actually achieved remission

doi: 10.1186/s13075-018-1600-5 31 ShenXWangCLiangNLiuZLiXZhuZJet al

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DHODH inhibition synergizes with DNA-demethylating agents in the treatment of myelodysplastic syndromes

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